Family resilience plays an important role in improving the well-being of preschool children with disabilities and their families. This study has explained the connotation and characteristics of family resilience of preschool children from the aspects of ecology, development and dynamic adaptability, and has revealed the generation mechanism of family resistance of preschool special children with disabilities from five aspects: guarantee mechanism for the bottom line, protection and compensation mechanism, pressure buffer mechanism, cooperation and communication mechanism, adjustment and transcendence mechanism. This paper probes into the cultivation path of family resilience of preschool special children at macro, meso and micro levels, including giving play to the role of the government in top-level design and strengthening the foundation of the family support and guarantee system, strengthening the responsibilities of communities and institutions/kindergartens, enhancing the external connections of families and providing compensation for the lacking resources, giving play to the subjective initiative of families and establishing social support networks among relatives and friends, strengthening the internal cohesion of families and constructing good family organizational models, and empowering the growth of family members and adhering to positive beliefs.